RESUMO
Nationwide monitoring of antimicrobial resistance in Campylobacter isolated from food-producing animals on farms was performed in Japan. A total of 468 Campylobacter isolates were obtained during the period from June 1999 to March 2001. Campylobacter species showed high frequencies of resistance to oxytetracycline and dihydrostreptomycin. The frequencies of resistance in Campylobacter coli to aminoglycosides, macrolides, tetracycline and quinolones were higher than those in Campylobacter jejuni to the same drugs. All of the C. jejuni isolates were susceptible to macrolide antibiotics, whereas 48.4% of the C. coli isolates were resistant to macrolides. Resistance to fluoroquinolones was observed in C. jejuni isolates from broilers (12%) and layers (2.6%), indicating that the level of fluoroquinolone resistance in Japan could be ranked as low.
Assuntos
Animais Domésticos/microbiologia , Antibacterianos/farmacologia , Infecções por Campylobacter/veterinária , Campylobacter/efeitos dos fármacos , Campylobacter/isolamento & purificação , Aminoglicosídeos/farmacologia , Animais , Campylobacter/classificação , Infecções por Campylobacter/epidemiologia , Infecções por Campylobacter/microbiologia , Campylobacter coli/classificação , Campylobacter coli/efeitos dos fármacos , Campylobacter coli/isolamento & purificação , Campylobacter jejuni/classificação , Campylobacter jejuni/efeitos dos fármacos , Campylobacter jejuni/isolamento & purificação , Bovinos , Galinhas , Sulfato de Di-Hidroestreptomicina/farmacologia , Farmacorresistência Bacteriana , Fluoroquinolonas/farmacologia , Japão/epidemiologia , Macrolídeos/farmacologia , Testes de Sensibilidade Microbiana , Oxitetraciclina/farmacologia , Quinolonas/farmacologia , Suínos , Resistência a TetraciclinaRESUMO
A nationwide investigation of antimicrobial susceptibility in Escherichia coli isolated from food-producing animals was performed in Japan. MICs of 18 antimicrobial agents were determined for a total of 1018 isolates. Higher resistance rates were observed against sulfadimethoxine, oxytetracycline and dihydrostreptomycin, followed by ampicillin and kanamycin. Resistance was more frequently observed among broiler isolates, followed by isolates from pigs. Almost 10% of broiler isolates were resistant to fluoroquinolones and extremely high MICs (100 mg/L) were observed. In general, antimicrobial resistance rates in E. coli have declined in recent years, with the exception of resistance to fluoroquinolones among broiler isolates, which has increased.
Assuntos
Resistência a Ampicilina , Microbiologia de Alimentos , Carne/microbiologia , Vigilância da População , Animais , Anti-Infecciosos/farmacologia , Bovinos , Galinhas , Fezes/microbiologia , Fluoroquinolonas , Japão/epidemiologia , Testes de Sensibilidade Microbiana , SuínosRESUMO
To isolate Campylobacter spp., the feces of healthy cattle, pigs, and broilers were examined between June 1999 and January 2000. Campylobacter lanienae strains were isolated from the feces of healthy pigs, but not from the feces of cattle or broilers. In six C. lanienae isolates, there was only 21-38% DNA-DNA homology to Campylobacter hyointestinalis subsp. lawsonii strain NCTC 12901. Thus, the primary host of C. lanienae is likely to be the pig and C. lanienae appears to be a species distinct from C. hyointestinalis subsp. lawsonii. In addition, an intervening sequence of 226 bp in the 16S rRNA gene was found in four isolates.
